Working at the initial stages of skin aging to improve skin thinning

　

The latest keyword in skin aging "skin thinning"

Aging skin symptoms such as wrinkles, sagging, and a decrease in firmness are caused by the degradation of the extracellular matrix (ECM) such as collagen in the dermis. Dermis with a degraded ECM becomes thinner, making the skin look thin. According to recent studies, the root cause of skin thinning is considered to be extracellular ATP produced by epidermal cells.
SpringMint is expected to suppress extracellular ATP excreted in the shallow areas of the skin and is an early factor to cause skin aging so it can provide a real sense of improvement in skin thinning.

　

　

Working at the initial stages of skin aging to improve skin thinning

# Suppressing production of extracellular ATP from aging epidermal cells
# Suppressing SASP expression induced by extracellular ATP
# Increasing the thickness of dermis (suppress thinning)
# Improving skin's elasticity

　

Mechanism of extracellular ATP and skin thinning

As cells aged, the extracellular ATP release increases. ATP released into the extracellular environment is a factor that transmits stimulation. Aging cells stimulated by extracellular ATP exhibit the senescence-associated secretory phenotype (SASP), secrete SASP-related factors and induce aging in surrounding cells. Fibroblasts in the dermis receiving these SASP-related factors secrete ECM degrading enzymes such as MMP, destroying the dermal layer and causing skin thinning of the dermis.

SpringMint uses organic peppermint.

SpringMint is manufactured using 1,3-Butylene Glycol which is obtained from Sugarcane.

　

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