The latest keyword
in skin aging
"skin thinning"
Natural Cosmetic Ingredient SpringMint
<Mentha Piperita (Peppermint) Leaf Extract>
- ANTI AGING
- ANTI WRINKLE
- SENSITIVE SKIN
- ORGANIC PLANT
Regain the former firmness and fullness of skin with natural aging care
Aging skin symptoms such as wrinkles, sagging, and a decrease in firmness are caused by the degradation of the extracellular matrix (ECM) such as collagen in the dermis. Dermis with a degraded ECM becomes thinner, making the skin look thin. According to recent studies, the root cause of skin thinning is considered to be extracellular ATP produced by epidermal cells.
SpringMint may assist in the improvement of skin thinning by suppressing extracellular ATP, which is a cause of skin aging, and is excreted in the superficial layers of the skin.
Special production
SpringMint utilizes organic peppermint from the historic oasis city of Faiyum, Egypt as one of its ingredients.
The 1,3-butylene glycol (BG) additionally used in this product is plant-based, coming from sugar cane rather than petroleum-based solvent extraction. SpringMint is made from 100% natural cosmetic ingredients.
Benefits
Working at the initial stages of skin aging to improve thinning
Suppressing production of extracellular ATP from aging epidermal cells
Suppressing SASP * expression induced by extracellular ATP
- SASP:Senescence-Associated Secretory Phenotype
Increasing the thickness of dermis (suppress thinning)
Improving skin's elasticity
Awards
PCHi 2021 Fountain Award in the anti-aging category
Features
Organic plant
IECIC2015
Japanese Quasi-Drug
Natural solvent
Paraben free
Not tested on animals
Mechanism of extracellular
ATP skin thinning
In aging cells, extracellular release of ATP increases. ATP released into the extracellular environment is a factor that transmits stimulation. Aging cells stimulated by extracellular ATP exhibit the senescence-associated secretory phenotype (SASP) , secrete SASP-related factors and induce aging in surrounding cells. Fibroblasts in the dermis receiving these SASP-related factors secrete ECM degrading enzymes such as MMP, destroying the dermal layer and causing skin thinning of the dermis.
Effects
The following test results demonstrate the usefulness of the product.
- Inhibiting the extracellular ATP release of aging epidermal cell
- Tested through the addition of SpringMint to aging human epidermal cells and measurement of extracellular ATP
- Inhibiting the extracellular ATP release by dryness stresses
- Discovered from the addition of SpringMint to human epidermal cells exposed to stress from dryness and measurement of extracellular ATP
- Inhibiting the extracellular ATP release by pH stresses
- Found from the addition of SpringMint to human epidermal cells exposed to stress in a slightly alkaline environment and measurement of extracellular ATP
- Suppressing SASP derivation by extracellular ATP
- Detected by measuring secretion of SASPs (IL-1beta, IL-6, and IL-8) from human epidermal cells due to the addition of extracellular ATP
- Increasing the thickness of dermis (suppress thinning)
- Found from the application of 1% SpringMint to the faces of 14 men and women in their 30s–60s experiencing the onset of aging and observation of dermis thickness four weeks later using ultrasound analysis
- Improving skin's elasticity
- Tested through the application of 1% SpringMint to the faces of 14 men and women in their 30s–60s experiencing the onset of aging and measurement of the skin's elasticity four weeks later
- Decreasing various types of wrinkles (Eye corner, smile line, and neck)
- Detected by the application of 1% SpringMint to the faces of 14 men and women in their 30s–60s experiencing the onset of aging and measurement of the size and depth of wrinkles on various parts around the face four weeks later
Contact us if you want to know more about the test results and how tests were conducted.
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Specifications
- Name
- SpringMint
- Description
- Light yellowish brown to brown liquid, having a characteristic odor
- INCI
- Butylene Glycol, Water, Mentha Piperita (Peppermint) Leaf Extract
- IECIC 2015 listing
- 丁二醇，水，辣薄荷(MENTHA PIPERITA) 叶提取物
- Recommended blending amount
- 1%
- Characteristics
- Liquid, Water soluble, Without alcohol, Without preservatives
Applications
The following test results demonstrate the usefulness of the product.
- Anti-aging products
- Wrinkle reduction
- Facial rejuvenation treatment
- Neck wrinkle treatment
- Scalp care
- Post aesthetic care
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Essays
-
- 24 MARCH 2019
- The 2019Annual meeting of JSBBA Involvement of extracellular ATP concentration in human skin thinning and suppression of thinning by peppermint leaf extract
-
- 1 April 2020
- SPC Vol.93 No.4 P84-86 Skin thinning : The latest anti-ageing target
-
- 21 OCTOBER 2020
- The 31st IFSCC Congress 2020 Yokohama Innovative wrinkle improvement strategy : a new approach by inhibiting extracellular ATP-mediated skin-thinning
-
- 1 OCTOBER 2021
- PERSONAL CARE Vol22 No9 P65-67 New approach to suppressing wrinkles
Frequently asked questions
References show that skin's thickness peaks at 20 years old, after which it gradually begins to thin.
Areas around the eyes, cheeks, neck, palms, and similar places where skin is thinner become susceptible to the effects of skin thinning, such as wrinkles like eye corner wrinkles, smile lines, and neck wrinkles.
Yes, it is believed that it occurs all over the body.
Peppermint has been around for a long time, and dried leaves from around 1,000 BC have been found in Egyptian pyramids.
It was highly valued by Greeks and Romans, and spread through western Europe in the 18th century. Peppermint has various effects mainly relating to medicine, and there are articles stating that it relieves gas, bloating, swelling, and severe stomachaches.
Yes, ATP works as a source of energy within cells.
However, when expelled outside of the cell, it is interpreted by the body as an indication of danger. Extracellular ATP in vivo causes exacerbation of immune response, the occurrence of inflammation and pain, and other such reactions.
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About us
Who we are
After the establishment in 1959, ICHIMARU PHARCOS has become a global leader in Research and Development of natural active ingredients for the cosmetic industry. Locating in Gifu prefecture, Japan, the company has gained reputation and trust from world leading cosmetic brands including small scale cosmetic manufacturers for efficient support and service. ICHIMARU PHARCOS provides more than 1,000 ingredients from natural resources to cosmetics and food industries all over the world.
What we do
ICHIMARU PHARCOS focuses primarily on the research and development of natural ingredients. Approximately 30 percent employees are research and development scientists. By cooperating with reputed universities and research institutes, we have established a secured research and development base. Taking into consideration the potential needs of customers regarding beauty and health, ICHIMARU PHARCOS develops new ingredients for cosmetics and health foods as well as creates new trends.
Areas of expertise
-
Active
Ingredients -
Sustainability
-
Skin Care
-
Scalp & Hair Care
-
Natural
Ingredients
Contact
Send us a message if you have any questions.
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