The latest keyword
in skin aging
"skin thinning"

Natural Cosmetic Ingredient SpringMint

<Mentha Piperita (Peppermint) Leaf Extract>

  • ANTI AGING
  • ANTI WRINKLE
  • SENSITIVE SKIN
  • ORGANIC PLANT

Regain the former firmness and fullness of skin with natural aging care

Aging skin symptoms such as wrinkles, sagging, and a decrease in firmness are caused by the degradation of the extracellular matrix (ECM) such as collagen in the dermis. Dermis with a degraded ECM becomes thinner, making the skin look thin. According to recent studies, the root cause of skin thinning is considered to be extracellular ATP produced by epidermal cells.
SpringMint may assist in the improvement of skin thinning by suppressing extracellular ATP, which is a cause of skin aging, and is excreted in the superficial layers of the skin.

Special production

SpringMint utilizes organic peppermint from the historic oasis city of Faiyum, Egypt as one of its ingredients.
The 1,3-butylene glycol (BG) additionally used in this product is plant-based, coming from sugar cane rather than petroleum-based solvent extraction. SpringMint is made from 100% natural cosmetic ingredients.

Benefits

Working at the initial stages of skin aging to improve thinning

01

Suppressing production of extracellular ATP from aging epidermal cells

02

Suppressing SASP * expression induced by extracellular ATP

  • SASP:Senescence-Associated Secretory Phenotype
03

Increasing the thickness of dermis (suppress thinning)

04

Improving skin's elasticity

Features

Organic plant

IECIC2015

Japanese Quasi-Drug

Natural solvent

Paraben free

Not tested on animals

Mechanism of extracellular
ATP skin thinning

In aging cells, extracellular release of ATP increases. ATP released into the extracellular environment is a factor that transmits stimulation. Aging cells stimulated by extracellular ATP exhibit the senescence-associated secretory phenotype (SASP) , secrete SASP-related factors and induce aging in surrounding cells. Fibroblasts in the dermis receiving these SASP-related factors secrete ECM degrading enzymes such as MMP, destroying the dermal layer and causing skin thinning of the dermis.

Effects

The following test results demonstrate the usefulness of the product.

IN VITRO
Inhibiting the extracellular ATP release of aging epidermal cell
Tested through the addition of SpringMint to aging human epidermal cells and measurement of extracellular ATP
IN VITRO
Inhibiting the extracellular ATP release by dryness stresses
Discovered from the addition of SpringMint to human epidermal cells exposed to stress from dryness and measurement of extracellular ATP
IN VITRO
Inhibiting the extracellular ATP release by pH stresses
Found from the addition of SpringMint to human epidermal cells exposed to stress in a slightly alkaline environment and measurement of extracellular ATP
IN VITRO
Suppressing SASP derivation by extracellular ATP
Detected by measuring secretion of SASPs (IL-1beta, IL-6, and IL-8) from human epidermal cells due to the addition of extracellular ATP
IN VIVO
Increasing the thickness of dermis (suppress thinning)
Found from the application of 1% SpringMint to the faces of 14 men and women in their 30s–60s experiencing the onset of aging and observation of dermis thickness four weeks later using ultrasound analysis
IN VIVO
Improving skin's elasticity
Tested through the application of 1% SpringMint to the faces of 14 men and women in their 30s–60s experiencing the onset of aging and measurement of the skin's elasticity four weeks later
IN VIVO
Decreasing various types of wrinkles (Eye corner, smile line, and neck)
Detected by the application of 1% SpringMint to the faces of 14 men and women in their 30s–60s experiencing the onset of aging and measurement of the size and depth of wrinkles on various parts around the face four weeks later

Contact us if you want to know more about the test results and how tests were conducted.

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Specifications

Name
SpringMint
Description
Light yellowish brown to brown liquid, having a characteristic odor
INCI
Butylene Glycol, Water, Mentha Piperita (Peppermint) Leaf Extract
IECIC 2015 listing
丁二醇,水,辣薄荷(MENTHA PIPERITA) 叶提取物
Recommended blending amount
1%
Characteristics
Liquid, Water soluble, Without alcohol, Without preservatives

Applications

The following test results demonstrate the usefulness of the product.

  • Anti-aging products
  • Wrinkle reduction
  • Facial rejuvenation treatment
  • Neck wrinkle treatment
  • Scalp care
  • Post aesthetic care

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Essays

  • 24 MARCH 2019
    The 2019Annual meeting of JSBBA Involvement of extracellular ATP concentration in human skin thinning and suppression of thinning by peppermint leaf extract
  • 1 April 2020
    SPC Vol.93 No.4 P84-86 Skin thinning : The latest anti-ageing target

Frequently asked questions

References show that skin's thickness peaks at 20 years old, after which it gradually begins to thin.

Areas around the eyes, cheeks, neck, palms, and similar places where skin is thinner become susceptible to the effects of skin thinning, such as wrinkles like eye corner wrinkles, smile lines, and neck wrinkles.

Yes, it is believed that it occurs all over the body.

Peppermint has been around for a long time, and dried leaves from around 1,000 BC have been found in Egyptian pyramids.
It was highly valued by Greeks and Romans, and spread through western Europe in the 18th century. Peppermint has various effects mainly relating to medicine, and there are articles stating that it relieves gas, bloating, swelling, and severe stomachaches.

Yes, ATP works as a source of energy within cells.
However, when expelled outside of the cell, it is interpreted by the body as an indication of danger. Extracellular ATP in vivo causes exacerbation of immune response, the occurrence of inflammation and pain, and other such reactions.

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About us

Who we are

After the establishment in 1959, ICHIMARU PHARCOS has become a global leader in Research and Development of natural active ingredients for the cosmetic industry. Locating in Gifu prefecture, Japan, the company has gained reputation and trust from world leading cosmetic brands including small scale cosmetic manufacturers for efficient support and service. ICHIMARU PHARCOS provides more than 1,000 ingredients from natural resources to cosmetics and food industries all over the world.

What we do

ICHIMARU PHARCOS focuses primarily on the research and development of natural ingredients. Approximately 30 percent employees are research and development scientists. By cooperating with reputed universities and research institutes, we have established a secured research and development base. Taking into consideration the potential needs of customers regarding beauty and health, ICHIMARU PHARCOS develops new ingredients for cosmetics and health foods as well as creates new trends.

Areas of expertise

  • Active
    Ingredients

  • Sustainability

  • Skin Care

  • Scalp & Hair Care

  • Natural
    Ingredients

Contact

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