Natural Cosmetic Ingredient HappiClov

Four leaves that make
the skin smile

  • ANTI AGING
  • SUSTAINABILITY

The need to smile again

Stress is a normal physiological response to an abnormal situation and is an integral part of our existence.
Our current life encounters a particular, unusual, and stressful reality that affects the psychological as well as the physical level.

Special production

In nature, the chance of finding a four-leaf clover is 1/10,000 ~1/100,000 (0.01%~0.001%).

But ICHIMARU PHARCOS found the «Happy four-leaf clover» Town, Tahara city, where developed a technique on how to grow four-leaf clover.

The technique is based on white clover mutations, by cuttings in a natural way, without GMO.

HappiClov is made from both leaves and flowers.

Benefits

Four leaves that make the skin smile

01
Increasing the expression
of DANCE
02
Increasing the expression of
ELASTIN
03
Lifting-up the corner of mouth
(smile effect)
04
Lifting-up the cheek

Features

  • IECIC2021
  • NATURAL
    SOLVENT
  • PARABEN
    FREE
  • NOT TESTED
    ON ANIMALS
  • SUSTAINABILITY

Mechanism of HappiClov

HappiClov up-regulates two factors important for
skin smiling, Elastin and DANCE.

  1. -Elastin works like a spring in the skin mattress.
  2. -DANCE aligns monomeric elastin to form elastin fiber.

Effects

The following test results demonstrate the usefulness of the product.

IN VITRO

Increasing
the expression of DANCE
Measured the mRNA level of human dermal fibroblast cultured with or without 1% HappiClov.

IN VITRO

Increasing
the expression of ELASTIN
Measured the mRNA level of human dermal fibroblast cultured with or without 1% HappiClov.

IN VIVO

Lifting-up
the corner of mouth
(smile effect)
3D skin analysis was performed after using facial lotion containing 1% HappiClov for 4 weeks.

IN VIVO

Lifting-up
the cheek
3D skin analysis was performed after using facial lotion containing 1% HappiClov for 4 weeks.

IN VITRO

Increasing
the secretion of
β-endorphin
Measured the protein secretion from human epidermal keratinocyte cultured with or without 1% HappiClov.

Specifications

Name
HappiClov
Description
Light yellow to yellowish brown liquid, with a characteristic odor
INCI
Butylene Glycol, Water, Trifolium Repens Extract
IECIC 2021 listing
丁二醇、水、白车轴草(TRIFOLIUM REPENS)提取物
Recommended blending amount
1%
Other
COSMOS approved, butylene glycol from sugar cane
Characteristics
Liquid, Water soluble, Without alcohol, Without preservatives

Applications

The following applications are recommended.

Facial care

anti-aging

Lip care and make-up

lip balm, lipstick

Body care

neck, breast, hands, dry area of skin

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Frequently asked questions

The material plant is a polyleafic strain 70% of which grows as more than four leaves. This strain was developed by repeated hybridization and stock division for ten years, without gene manipulation.​

DANCE promotes tropoelastin polymerization on microfibril to form elastin fiber. However, the amount of DANCE is reduced depending on aging and UV. HappiClov promotes expression of DANCE and appropriate elastin fiber formation.​

β-Endorphin not only promotes cell proliferation of keratinocyte and dermal fibroblast but also improves epidermal turnover and barrier function.​

HappiClov contributes to following goals:​
Goal 8. DECENT WORK AND ECONOMIC GROWTH (support for local town revitalization activities and welfare facilities)
Goal 12. RESPONSIBLE PRODUCTION AND CONSUMPTION (use of safe and secure by-product)
Goal 15. LIFE ON LAND (use of not wild species but cultivated species, preservation of local species)​

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