Natural Cosmetic Ingredient HappiClov
Four leaves that make
the skin smile
-
ANTI AGING
-
SUSTAINABILITY
The need to smile again
Stress is a normal physiological response to an abnormal situation and is an integral part of our existence.
Our current life encounters a particular, unusual, and stressful reality that affects the psychological as well as the physical level.


Special production
In nature, the chance of finding a four-leaf clover is 1/10,000 ~1/100,000 (0.01%~0.001%).
But ICHIMARU PHARCOS found the «Happy four-leaf clover» Town, Tahara city, where developed a technique on how to grow four-leaf clover.
The technique is based on white clover mutations, by cuttings in a natural way, without GMO.
HappiClov is made from both leaves and flowers.
Benefits
Four leaves that make the skin smile
of DANCE
ELASTIN
(smile effect)
Features
-
IECIC2021
-
NATURAL
SOLVENT -
PARABEN
FREE -
NOT TESTED
ON ANIMALS -
SUSTAINABILITY
Mechanism of HappiClov
HappiClov up-regulates two factors important for
skin smiling, Elastin and DANCE.
- -Elastin works like a spring in the skin mattress.
- -DANCE aligns monomeric elastin to form elastin fiber.

Effects
The following test results demonstrate the usefulness of the product.
IN VITRO
- Increasing
the expression of DANCE - Measured the mRNA level of human dermal fibroblast cultured with or without 1% HappiClov.
IN VITRO
- Increasing
the expression of ELASTIN - Measured the mRNA level of human dermal fibroblast cultured with or without 1% HappiClov.
IN VIVO
- Lifting-up
the corner of mouth
(smile effect) - 3D skin analysis was performed after using facial lotion containing 1% HappiClov for 4 weeks.
IN VIVO
- Lifting-up
the cheek - 3D skin analysis was performed after using facial lotion containing 1% HappiClov for 4 weeks.
IN VITRO
- Increasing
the secretion of
β-endorphin - Measured the protein secretion from human epidermal keratinocyte cultured with or without 1% HappiClov.
Specifications
- Name
- HappiClov
- Description
- Light yellow to yellowish brown liquid, with a characteristic odor
- INCI
- Butylene Glycol, Water, Trifolium Repens Extract
- IECIC 2021 listing
- 丁二醇、水、白车轴草(TRIFOLIUM REPENS)提取物
- Recommended blending amount
- 1%
- Other
- COSMOS approved, butylene glycol from sugar cane
- Characteristics
- Liquid, Water soluble, Without alcohol, Without preservatives
Applications
The following applications are recommended.
Facial care
anti-aging
Lip care and make-up
lip balm, lipstick
Body care
neck, breast, hands, dry area of skin

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CONTACTFrequently asked questions
The material plant is a polyleafic strain 70% of which grows as more than four leaves. This strain was developed by repeated hybridization and stock division for ten years, without gene manipulation.
DANCE promotes tropoelastin polymerization on microfibril to form elastin fiber. However, the amount of DANCE is reduced depending on aging and UV. HappiClov promotes expression of DANCE and appropriate elastin fiber formation.
β-Endorphin not only promotes cell proliferation of keratinocyte and dermal fibroblast but also improves epidermal turnover and barrier function.
HappiClov contributes to following goals:
Goal 8. DECENT WORK AND ECONOMIC GROWTH (support for local town revitalization activities and welfare facilities)
Goal 12. RESPONSIBLE PRODUCTION AND CONSUMPTION (use of safe and secure by-product)
Goal 15. LIFE ON LAND (use of not wild species but cultivated species, preservation of local species)
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Contact
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CONTACT