Vegan
Proteoglycan

Wisdom
from traditional herb
for anti aging care

BSB Innovation Award

  • ANTI AGING
  • ANTI WRINKLE

Fibroblast and ECM «foundation of the skin» decrease
with aging

Dermis consists of fibroblast and ECM (Extracellular Matrix)
forming foundation of the skin. Appropriate proportions of fibroblasts and ECM components are necessary to keep a youthful appearance.
Dermal fibroblast and collagen are known to decrease with aging, causing dermal volume loss and deep wrinkle.

Fibroblast:
Dermal cell that produces ECM components like
collagen, proteoglycans, and more.

ECM Components

  • collagen:
    Proteins that build
    the dermal structure.
  • Proteoglycans:
    Glycoproteins that
    activate cells and
    keep skin elasticity.

Special production

Anogeissus latifolia
Soluble Proteoglycan extracted from ghatti gum was found to promote both fibroblast proliferation and collagen production.

Benefits

Wisdom from traditional herb for anti-aging care

01
Promoting proliferation of dermal fibroblast
02
Increasing collagen density
03
Reducing wrinkle
04
Improving skin texture
05
Reducing age spots

Awards

BSB Innovation Award

BSB Innovation Award 2023 first prize in the Section: "Matrix, Sebum controlling,
Cell protection, Oral care", on Natural Products / Raw Materials category

Features

  • IECIC2021
  • Natural solvent
  • Not tested on animals
  • Paraben free

Our innovation about VeganProteoglycan

All animals, fishes and plants have proteoglycans in their body.
Humans used to apply proteoglycans as an effective ingredient.
Animal-derived proteoglycan has been used for cosmetic market with the INCI name, “Soluble Proteoglycan”. 

Effects

The following test results demonstrate the usefulness of the product.

IN VITRO

Promoting proliferation of
dermal fibroblast
Measured the amount of human dermal fibroblast cultured with and without 0.5% VeganProteoglycan.

IN VITRO

Increasing collagen
Production
Measured Collagen production in human dermal fibroblast cultured with and without 0.5% VeganProteoglycan by ELISA.

IN VIVO

Increasing
collagen density
Collagen density was visualized after using facial lotion containing 0.5%
VeganProteoglycan for 4 weeks.

IN VIVO

Reducing wrinkle
(smile lines, crow’s feet)
3D skin analysis was performed after using facial lotion containing 0.5%
VeganProteoglycan for 4 weeks.

IN VIVO

Improving
skin texture
Skin texture was visualized after using facial lotion containing 0.5%
VeganProteoglycan for 4 weeks.

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Specifications

Name
VeganProteoglycan
Description
Colorless to light yellow liquid, slightly characteristic odor
INCI
Water, Butylene Glycol, Soluble Proteoglycan
IECIC 2021 listing
水、丁二醇、可溶性蛋白多糖
Recommended blending amount
0.5%
Other
COSMOS approved, butylene glycol from sugar cane, HALAL certified
Characteristics
Liquid, Water soluble, Without alcohol, Without preservatives

Applications

The following applications are recommended.

Facial care

anti-aging, smile line
products

Eye care

under eye care

Body care

hand, neck

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Frequently asked questions

Proteoglycans are essential components of ECM(Extracellular Matrix) in dermis. Structure of Proteoglycans is that Glycoprotein in which sugar chains called glycosaminoglycans (GAG) are covalently bonded to the core protein. Roles of Proteoglycans is storing lots of water, keeping skin moisture and elasticity and activating cell growth and differentiation.  

Animal-derived proteoglycan has been used for cosmetic market. Therefore, some customers who are sensitive to ingredients derived from animals cannot use Proteoglycan. We have developed Proteoglycan derived from ghatti tree and now we are able to suggest proteoglycan to all customers. 

Improves wrinkles and reduction of age spots by increasing collagen density. 

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