Vegan
Proteoglycan
Wisdom
from traditional herb
for anti aging care
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ANTI AGING
-
ANTI WRINKLE
Fibroblast and ECM «foundation of the skin» decrease
with aging
Dermis consists of fibroblast and ECM (Extracellular Matrix)
forming foundation of the skin. Appropriate proportions of fibroblasts and ECM components are necessary to keep a youthful appearance.
Dermal fibroblast and collagen are known to decrease with aging, causing dermal volume loss and deep wrinkle.

Fibroblast:
Dermal cell that produces ECM components like
collagen, proteoglycans, and more.
ECM Components
- collagen:
Proteins that build
the dermal structure. - Proteoglycans:
Glycoproteins that
activate cells and
keep skin elasticity.


Special production
Anogeissus latifolia
Soluble Proteoglycan extracted from ghatti gum was found to promote both fibroblast proliferation and collagen production.
Benefits
Wisdom from traditional herb for anti-aging care
Awards

BSB Innovation Award 2023 first prize in the Section: "Matrix, Sebum controlling,
Cell protection, Oral care", on Natural Products / Raw Materials category
Features
-
IECIC2021
-
Natural solvent
-
Not tested on animals
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Paraben free
Our innovation about VeganProteoglycan
All animals, fishes and plants have proteoglycans in their body.
Humans used to apply proteoglycans as an effective ingredient.
Animal-derived proteoglycan has been used for cosmetic market with the INCI name, “Soluble Proteoglycan”.

Effects
The following test results demonstrate the usefulness of the product.
IN VITRO
- Promoting proliferation of
dermal fibroblast - Measured the amount of human dermal fibroblast cultured with and without 0.5% VeganProteoglycan.
IN VITRO
- Increasing collagen
Production - Measured Collagen production in human dermal fibroblast cultured with and without 0.5% VeganProteoglycan by ELISA.
IN VIVO
- Increasing
collagen density - Collagen density was visualized after using facial lotion containing 0.5%
VeganProteoglycan for 4 weeks.
IN VIVO
- Reducing wrinkle
(smile lines, crow’s feet) - 3D skin analysis was performed after using facial lotion containing 0.5%
VeganProteoglycan for 4 weeks.
IN VIVO
- Improving
skin texture - Skin texture was visualized after using facial lotion containing 0.5%
VeganProteoglycan for 4 weeks.
Contact
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CONTACTSpecifications
- Name
- VeganProteoglycan
- Description
- Colorless to light yellow liquid, slightly characteristic odor
- INCI
- Water, Butylene Glycol, Soluble Proteoglycan
- IECIC 2021 listing
- 水、丁二醇、可溶性蛋白多糖
- Recommended blending amount
- 0.5%
- Other
- COSMOS approved, butylene glycol from sugar cane, HALAL certified
- Characteristics
- Liquid, Water soluble, Without alcohol, Without preservatives
Applications
The following applications are recommended.
Facial care
anti-aging, smile line
products
Eye care
under eye care
Body care
hand, neck

Get our catalog
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CONTACTFrequently asked questions
Proteoglycans are essential components of ECM(Extracellular Matrix) in dermis. Structure of Proteoglycans is that Glycoprotein in which sugar chains called glycosaminoglycans (GAG) are covalently bonded to the core protein. Roles of Proteoglycans is storing lots of water, keeping skin moisture and elasticity and activating cell growth and differentiation.
Animal-derived proteoglycan has been used for cosmetic market. Therefore, some customers who are sensitive to ingredients derived from animals cannot use Proteoglycan. We have developed Proteoglycan derived from ghatti tree and now we are able to suggest proteoglycan to all customers.
Improves wrinkles and reduction of age spots by increasing collagen density.
Similar products
A variety of other lineups popular with customers is also available.

- BabyColla
- Raise collagen for the softness like a baby skin
- Anti-aging
- Anti-wrinkle

- SpringMint
- Increasing the thickness of dermis (suppress thinning)
- Anti-aging
- Anti-wrinkle
- Sensitive skin

- OUGON Liquid B
- Anti-pollution (PM2.5, Tobacco smoke, etc.)
- Anti-aging
- Anti-wrinkle
- Anti-pollution

- Absorage
- Prevention glycation leads transparent skin
- Anti-aging
- Anti-wrinkle
- Lightening

- CUREBERRY
- Protection of cell against Blue light / Activation of cell power
- Anti-aging
- Anti-wrinkle
- Lightening
- Moisturizing

- CUREPASSION
- Improving dermal lymphatic system for skin puffiness and dullness
- Anti-aging
- Slimming
- Anti-wrinkle
- Scalp care
Contact
Send us a message if you have any questions.
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CONTACT